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Invitrogen™ FUS Polyclonal Antibody

Product Code. 16589311
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Quantity:
100 μL
Unit Size:
100µL
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16589311 100 μL 100µL
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Product Code. 16589311 Supplier Invitrogen™ Supplier No. PA596477

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: TIESVADYFK QIGIIKTNKK TGQPMINLYT DRETGKLKGE ATVSFDDPPS AKAAIDWFDG KEFSGNPIKV SFATRRADFN RGGGNGRGGR GRGGPMGRGG YGGGGSGGGG RGGFPSGGGG GGGQQRAGDW KCPNPTCENM NFSWRNECNQ CKAPKPDGPG GGPGGSHMGG NYGDDRRGGR GGYDRGGYRG RGGDRGGFRG GRGGGDRGGF GPGKMDSRGE HRQDRRERPY; Positive Samples: U-937, Jurkat; Cellular Location: Nucleus.

This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
TRUSTED_SUSTAINABILITY

Specifications

Antigen FUS
Applications ELISA, Immunoprecipitation, Western Blot, Immunocytochemistry, Western Blot
Classification Polyclonal
Concentration 0.82 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene FUS
Gene Accession No. P35637, P56959
Gene Alias 16) in malignant liposarcoma); 16) malignant liposarcoma; 75 kDa DNA-pairing protein; ALS6; D430004D17Rik; D930039C12Rik; ETM4; FUS; FUS RNA binding protein; Fus1; fused in sarcoma; fused in sarcoma RNA binding protein; fusion (involved in t(12; fusion gene in myxoid liposarcoma; fusion, derived from t(12; fusion, derived from t(12;16) malignant liposarcoma; fus-like protein; heterogeneous nuclear ribonucleoprotein P2; hnRNP P2; HNRNPP2; oncogene FUS; Oncogene TLS; pigpen protein; POMP75; Protein pigpen; RNA-binding protein FUS; TLS; translocated in liposarcoma; translocated in liposarcoma protein
Gene Symbols FUS
Host Species Rabbit
Immunogen Recombinant protein (or fragment)
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 233908, 2521, 317385
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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