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Invitrogen™ GDF5 Monoclonal Antibody (90509)
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Product Code. 30534736
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Quantity:
500 μg
Unit Size:
500µg
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30534736 500 μg 500µg
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Product Code. 30534736 Supplier Invitrogen™ Supplier No. MA561960

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Rat Monoclonal Antibody

Reconstitute at 0.5 mg/mL in sterile PBS.

GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Hunter-Thompson type dwarfism and in Grebe Syndrome, which is characterized by short stature, extra digits, and short and deformed extremities. The mature and functional form of GDF-5 is a homodimer of two 120 amino-acid polypeptide chain (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino acid signal peptide and a 354 amino acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GDF5
Applications Western Blot
Classification Monoclonal
Clone 90509
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with trehalose and no preservative
Gene GDF5
Gene Accession No. P43027
Gene Alias BDA1C; Bmp14; BMP-14; Bone morphogenetic protein 14; bp; brachypodism; brp; Cartilage-derived morphogenetic protein 1; cartilage-derived morphogenetic protein-1; CDMP1; Cdmp-1; GDF5; GDF-5; growth differentiation factor 5; growth/differentiation factor 5; H-GDF-5; LAP4; LAP-4; Lipopolysaccharide-associated protein 4; LPS-associated protein 4; OS5; radotermin; SYM1B; SYNS2
Gene Symbols GDF5
Host Species Rat
Immunogen E. coli-derived recombinant mouse GDF-5/BMP-14, Ala376-Arg495.
Purification Method Protein A/G
Quantity 500 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 14563
Target Species Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Lyophilized
Isotype IgG2a
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