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Invitrogen™ GPR20 Polyclonal Antibody

Product Code. 11305733
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Quantity:
100 μL
Unit Size:
100µL
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11305733 100 μL 100µL
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Product Code. 11305733 Supplier Invitrogen™ Supplier No. PA3068

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Description

Rabbit Polyclonal Antibody

PA3-068 detects GPR20 from mouse samples. PA3-068 has been successfully used in Western blot, immunocytochemistry, and immunohistochemistry procedures. By Western blot, this antibody detects a 39 kDa protein corresponding to mouse GPR20. The PA3-068 antigen is the COOH-terminal amino acids of mouse GPR20 (338-358) IHILSIGSHTLTQPLTNGPEP coupled to KLH.

G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors translate extracellular signals into intracellular signals (G protein activation) and they respond to a variety of signaling molecules, such as hormones and neurotransmitters. GPR20 is a 358 amino acid membrane protein that constitutively activates G(i) proteins without ligand stimulation. Also, GPR20 may be involved in the control of intracellular cAMP levels and mitogenic signaling. Interestingly, GPR20 is expressed in liver and certain regions of the brain, including putamen, caudate and thalamus, but is not expressed in hypothalamus, pons and frontal cortex.
TRUSTED_SUSTAINABILITY

Specifications

Antigen GPR20
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration Conc. Not Determined
Conjugate Unconjugated
Formulation whole serum with 0.02% sodium azide
Gene GPR20
Gene Accession No. Q8BYC4
Gene Alias A430106B11Rik; CTD-3064M3.3; G protein-coupled receptor 20; G protein-coupled receptor 5-1; G protein-coupled receptor GPR20; Gpcr5-1; GPR20; G-protein coupled receptor 20; P2Y4
Gene Symbols GPR20
Host Species Rabbit
Immunogen COOH-terminal amino acids of mouse GPR20 (338-358) IHILSIGSHTLTQPLTNGPEP coupled to KLH.
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 239530
Target Species Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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