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HDAC9 Mouse anti-Human, Clone: OTI5B8, liquid, TrueMAB™

Produktkod. 17585213
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Quantity:
100 μL
Förpackningsstorlek:
100µL
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17585213 100 μL 100µL
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Produktkod. 17585213 Leverantör Origene Technologies Leverantörsnummer TA805323
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Estimated Shipment: 04-09-2026
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Beskrivning

Mouse Monoclonal Antibody

HDAC-9 is a histone deacetylase with an important role in the regulation of gene expression and hematopoiesis. A nuclear protein, HDAC-9 belongs to the histone deacetylase family with several isoforms and is inhibited by Trichostatin A (TSA) and suberoylanilide hydroxamic acid. It helps in deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4) and gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. MEF2-dependent transcription is repressed by HDAC-9 by recruiting HDAC-1 and/or HDAC-3. It also inhibits skeletal myogenesis and is involved in heart development. Ubiquitous but variable expression is seen in brain and other tissues like heart, pancreas and also in human bladder carcinoma cells. Lack of HDAC-9 protein is found in a family with Peters anomaly, a central corneal leukoma.

Specifikationer

Antigen HDAC9
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI5B8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene HDAC9
Gene Accession No. Q9UKV0
Gene Alias HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR
Gene Symbols HDAC9
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 181-460 of human HDAC9 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 9734
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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