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Invitrogen™ IRAK-M Polyclonal Antibody
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Product Code. 16547191
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Quantity:
100 μL
Unit Size:
100µL
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16547191 100 μL 100µL
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Product Code. 16547191 Supplier Invitrogen™ Supplier No. PA589217

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: VLTGCRVVLD DPKHIQLRDL LRELMEKRGL DSCLSFLDKK VPPCPRNFSA KLFCLAGRCA ATRAKLRPSM DEVLNTLEST QASLYFAEDP PTSLKSFRCP SPLFLENVPS IPVEDDESQN NNLLPSDEGL RIDRMTQKTP FECSQSEVMF LSLDKKPESK RNEEACNMPS SSCEESWFPK YIVPSQDLRP YKVNIDPSSE APGHSCRSRP VESSCSSKFS WDEYEQYKKE; Positive Samples: HL-60, THP-1, Mouse lung, Rat lung.

IRAK3 serine/threonine kinase or interleukin-1 receptor-associated kinase 3 is a member of the interleukin-1 receptor-associated kinase protein family which are essential components of the Toll/IL-R immune signal transduction pathways. IRAK3 is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. IRAK3 mediates critical aspects of innate immunity that result in an immunocompromised state during sepsis. Mutations in IRAK3 are associated with a susceptibility to asthma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen IRAK-M
Applications ELISA, Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 2.24 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.09% sodium azide; pH 7.3
Gene IRAK3
Gene Accession No. Q8K4B2, Q9Y616
Gene Alias 4833428C18Rik; AI563835; ASRT5; FLJ13601; IL-1 receptor-associated kinase M; interleukin 1 receptor associated kinase 3; interleukin-1 receptor-associated kinase 3; IRAK3; IRAK-3; IRAKM; IRAK-M
Gene Symbols IRAK3
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 367-596 of human IRAK3 (NP_0091302).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11213, 314870, 73914
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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