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Tocris Bioscience™ JNJ 10191584 maleate

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Quantity:
10 mg
50 mg
Unit Size:
10mg
50mg
Description
Highly selective histamine H4 receptor silent antagonist; binds with high affinity to the human H4 receptor (Ki = 26 nM). > 540-fold selective over the H3 receptor (Ki = 14.1 μM). Inhibits mast cell and eosinophil chemotaxis in vitro with IC50 values of 138 and 530 nM respectively. Orally active in vivo.
Specifications
Specifications
| Quantity | 50 mg |
| Formula Weight | 394.81 |
| Purity | >99% |
| Molecular Weight (g/mol) | 396.83 |
| Chemical Name or Material | JNJ 10191584 maleate |
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