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Thermo Scientific Chemicals L-Leucine, 99%

Product Code. 10274980 Shop All Thermo Scientific Chemicals Products
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Product Code. 10274980

Brand: Thermo Scientific Chemicals 125121000

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Description

L-Leucine, CAS # 61-90-5, is a branched-chain aliphatic essential amino acid in humans that is important for protein synthesis and many metabolic functions. | CAS: 61-90-5 | C6H13NO2 | 131.18 g/mol

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

  • L-Leucine is an essential amino acid that has an important role in the growth and repair of muscle and bone tissue
  • It functions to preserve muscle glycogen and helps to prevent the breakdown of muscle proteins after trauma or severe stress
  • It is also involved in hemoglobin formation and metabolic functions. This amino acid cannot be synthesized to meet the body's needs from simpler molecules, and therefore must be provided in the diet.
  • L-Leucine stimulates protein synthesis by the initiation of mRNA translation

Applications

  • L-Leucine is used in the biosynthesis of proteins
  • In vivo studies show that L-Leucine can be used when gene defects lead to an organism's inability to metabolize the amino acid phenylalanine
  • This compound also contributes to the regulation of blood-sugar levels, growth hormone production, and wound healing
  • In research experiments this compound has been used as an activator of the mammalian target of rapamycin (mTOR)
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 61-90-5
Molecular Formula C6H13NO2
Molecular Weight (g/mol) 131.18
MDL Number MFCD00002617
InChI Key ROHFNLRQFUQHCH-MLHKIVSYNA-N
Synonym l-leucine, leucine, s-leucine, s-2-amino-4-methylpentanoic acid, h-leu-oh, 2s-2-amino-4-methylpentanoic acid, s-+-leucine, leucin, l-norvaline, 4-methyl, s-2-amino-4-methylvaleric acid
PubChem CID 6106
ChEBI CHEBI:15603
IUPAC Name (2S)-2-amino-4-methylpentanoic acid
SMILES CC(C)C[C@H](N)C(O)=O

Specifications

Melting Point 286.0°C to 288.0°C
Specific Rotation + 15.40
Solubility Information Solubility in water: 22.4g/L (20°C). Other solubilities: 10.9g/L acetic acid, slightly soluble in alcohol, insoluble in ether
Sublimation Point 145.0 °C
Specific Rotation Condition + 15.40 (20.00°C c=4, 6N HCl)
Quantity 100 g
Formula Weight 131.17
Chemical Name or Material L-Leucine

RUO – Research Use Only

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