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LAP (Latency Associated peptide) Monoclonal Antibody (VB3A9), Functional Grade, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 16-9823-025
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Description
This VB3A9 monoclonal antibody recognizes human latency-associated peptide (LAP), also known as the TGF-beta propeptide. Human LAP is a homodimer of 65-75 kDa that is non-covalently associated with TGF-beta and this complex is also referred to as the small latent complex (SLC). LAP can be covalently associated with latent TGF-beta binding proteins (LTBP) through disulfide bonds, forming the large latent complex (LLC). The association of LAP with TGF-beta facilitates its secretion and also renders TGF-beta inactive. VB3A9 has been reported to cross-react with Non-human Primate LAP, but does not cross-react with mouse LAP. Applications Reported: This VB3A9 antibody has been reported for use in immunoblotting (WB) and immunoprecipitation. Applications Tested: This VB3A9 antibody has been tested by immunoblot analysis of human platelets under reducing conditions at 5 μg/mL. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/ μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.
LAP (Latency Associated peptide) Monoclonal antibody specifically detects LAP (Latency Associated peptide) in Human samples. It is validated for Immunoprecipitation, Western Blot
Specifications
| LAP (Latency Associated peptide) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative; pH 7.2 | |
| P01137 | |
| Mouse | |
| 25 mg | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
| Immunoprecipitation, Western Blot | |
| VB3A9 | |
| Functional Grade | |
| TGFB1 | |
| CED; DPD1; LAP; Latency-associated peptide; prepro-transforming growth factor beta-1; regulatory protein; TGFB; TGFB1; Tgfb-1; TGFbeta; TGF-beta 1; TGFbeta1; TGF-beta1; TGF-beta-1; transforming growth factor beta 1; transforming growth factor beta-1; Transforming growth factor beta-1 proprotein; transforming growth factor, beta 1; transforming growth factor-beta 1 | |
| Affinity chromatography | |
| RUO | |
| 7040 | |
| 4° C | |
| Liquid |
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