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Invitrogen™ MAPK15 Polyclonal Antibody
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Product Code. 16632185 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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16632185 100 μL 100µL
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Product Code. 16632185 Supplier Invitrogen™ Supplier No. PA5105740

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total ERK8.

The ERKs are a subfamily of the MAPKs that have been implicated in cell growth and differentiation. Extracellular signal-regulated kinase 8 (Erk8) is a large MAP kinase whose activity is controlled by serum and the c-Src non-receptor tyrosine kinase. ERK8 down-regulates transactivation of the glucocorticoid receptor through Hic-5 and can negatively regulate transcriptional co-activation of androgen receptor and GRalpha by Hic-5 in a kinase-independent manner, suggesting a broader role for ERK8 in the regulation of nuclear receptors beyond estrogen receptor alpha. Erk8 is a novel effector of RET/PTC3 and, therefore, RET biological functions.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MAPK15
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MAPK15
Gene Accession No. Q80Y86, Q8TD08
Gene Alias BC048082; EC 2.7.11.24; ERK7; ERK-7; ERK8; ERK-8; extracellular regulated kinase 8 delta; extracellular signal regulated kinase 8; extracellular signal-regulated kinase 7; Extracellular signal-regulated kinase 8; MAP kinase 15; MAPK 15; Mapk15; Mitogen-activated protein kinase 15
Gene Symbols MAPK15
Host Species Rabbit
Immunogen A synthesized peptide derived from human MAPK15(Accession Q8TD08), corresponding to amino acid residues V151-M201.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 225689, 332110
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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