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Invitrogen™ MAPKAPK3 Recombinant Rabbit Monoclonal Antibody (K01_2N31)

Description
MAPKAPK3 Recombinant Monoclonal Antibody for Western Blot
MAPKAPK3 functions as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. MAPKAPK3 was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. MAPKAPK3 was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation.
Specifications
Specifications
| Antigen | MAPKAPK3 |
| Applications | Western Blot |
| Classification | Recombinant Monoclonal |
| Clone | K01_2N31 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | 50mM tris glycine with 0.05% BSA, 40% glycerol, 150mM NaCl and 0.01% sodium azide; pH 7.4 |
| Gene | MAPKAPK3 |
| Gene Accession No. | Q16644 |
| Gene Alias | 3PK; AI874665; chromosome 3p kinase; MAP kinase-activated protein kinase 3; MAPK-activated protein kinase 3; MAPKAP kinase 3; MAPKAP3; MAPKAPK3; MAPKAP-K3; MAPKAPK-3; MapkKapk3; mitogen activated protein kinase-activated protein kinase 3; mitogen-activated protein kinase-activated protein kinase 3; MK3; MK-3; OTTHUMP00000210806; OTTHUMP00000210807 |
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