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Invitrogen™ MGST1 Monoclonal Antibody (14H2)

Description
Positive Control: SiHa cell, HepG2 cell, A549 cell, U937 cell, rat kidney tissue, human liver carcinoma tissue, human colon tissue, human placenta tissue, mouse liver tissue, MCF-7 cell.
The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, two of which are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. Other family members, demonstrating glutathione S-transferase and peroxidase activities, are involved in cellular defense against toxic, carcinogenic, and pharmacologically active electrophilic compounds. This gene encodes a protein that catalyzes the conjugation of glutathione to electrophiles and the reduction of lipid hydroperoxides. This protein is localized to the endoplasmic reticulum and outer mitochondrial membrane where it is thought to protect these membranes from oxidative stress.
Specifications
Specifications
| Antigen | MGST1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Western Blot |
| Classification | Monoclonal |
| Clone | 14H2 |
| Concentration | 2 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol, 0.2% BSA and 0.05% sodium azide; pH 7.4 |
| Gene | MGST1 |
| Gene Accession No. | P10620 |
| Gene Alias | 1500002K10Rik; glutathione S-transferase; glutathione S-transferase 12; Gst; GST12; MGC14525; MGST; mGST1; MGST-I; Microsomal glutathione S-transferase 1; microsomal glutathione S-transferase 1-like protein; microsomal glutathione-S-transferase; microsomal GST-1; Microsomal GST-I |
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