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Invitrogen™ MMP28 Polyclonal Antibody
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Product Code. 16626644
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Quantity:
100 μL
Unit Size:
100µL
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16626644 100 μL 100µL
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Product Code. 16626644 Supplier Invitrogen™ Supplier No. PA5100157

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total MMP28.

Epilysin, also known as matrix metalloproteinase-28 (MMP-28), is a secreted protein that belongs to the peptidase M10A family. Matrix metalloproteinase proteins are responsible for the breakdown of the extracellular matrix which is important for normal physiological processes such as tissue remodeling, reproduction and embryonic development. Epilysin is produced by proliferating keratinocytes and is responsible for mediating the degradation of casein. Its expression is upregulated in response to injury of the skin suggesting that Epilysin may be involved in tissue repair and homeostasis. In addition, Epilysin may function predominantly in the nervous system. Incubation of Epilysin with rat embryonic brain tissue results in the degradation of myelin proteins. In Xenopus, Epilysin localizes to nerves and is upregulated during neurulation. This suggests that Epilysin plays an evolutionarily conserved role in neural development and may be involved in modulating the axonal-glial extracellular environment.
TRUSTED_SUSTAINABILITY

Specifications

Antigen MMP28
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene MMP28
Gene Accession No. Q9H239
Gene Alias D130023P12; Epilysin; matrix metallo protease; matrix metallopeptidase 28; matrix metallopeptidase 28 (epilysin); matrix metalloprotease MMP25; matrix metalloproteinase 28 (epilysin); matrix metalloproteinase-28; MM28; MMP; MMP25; MMP-25; Mmp28; MMP-28; MMPs; PRO4339; UNQ1893; UNQ1893/PRO4339
Gene Symbols MMP28
Host Species Rabbit
Immunogen A synthesized peptide derived from human MMP28(Accession Q9H239), corresponding to amino acid residues V291-I341.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 118453, 303384, 79148
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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