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PMS2, Mouse, Clone: 349.29.5.2, Abnova™

Product Code. 16005426
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Quantity:
100 μg
Unit Size:
100µg
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16005426 100 μg 100µg
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Product Code. 16005426 Supplier Abnova Supplier No. MAB2089.100ug

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Description

Mouse monoclonal antibody raised against partial recombinant PMS2.

This gene is one of the PMS2 gene family members found in clusters on chromosome 7. The product of this gene is involved in DNA mismatch repair. It forms a heterodimer with MLH1 and this complex interacts with other complexes bound to mismatched bases. Mutations in this gene are associated with hereditary nonpolyposis colorectal cancer, Turcot syndrome, and are a cause of supratentorial primitive neuroectodermal tumors. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq

Specifications

Antigen PMS2
Applications ELISA, Western Blot
Classification Monoclonal
Clone 1204
Conjugate Unconjugated
Description Mouse monoclonal antibody raised against partial recombinant PMS2.
Dilution ELISA (1:5000-1:20000) Western Blot (1:500-1:2000) The optimal working dilution should be determined by the end user.
Formulation In 20mM KH2PO4, 150mM NaCl, pH 7.2 (0.01% sodium azide)
Gene PMS2
Gene Alias HNPCC4/PMS2CL/PMSL2
Gene Symbols PMS2
Host Species Mouse
Immunogen Recombinant protein corresponding to the first 133 amino acids of human PMS2.
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 5395
Test Specificity This is an protein A purified antibody directed against PMS2-134 and reacts with full length version of PMS2 in human and hamster tissues. The epitope was putatively mapped to amino acids 58-81 of human PMS2.
Target Species Chimpanzee, Human, Mouse, Rat
Content And Storage Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Form Liquid
Isotype IgG1 κ
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