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Invitrogen™ NF1 Polyclonal Antibody

Beskrivning
Antibody detects endogenous levels of total NF1.
The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
Specifikationer
Specifikationer
| Antigen | NF1 |
| Applications | Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | NF1 |
| Gene Accession No. | P21359, P97526, Q04690 |
| Gene Alias | AW494271; DKFZp686J1293; E030030H24Rik; FLJ21220; neurofibromatosis 1; Neurofibromatosis type 1; neurofibromatosis-related protein NF-1; Neurofibromin; neurofibromin 1; Neurofibromin truncated; NF1; Nf-1; NFNS; VRNF; WSS |
| Gene Symbols | NF1 |
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Produkttitel
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