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Invitrogen™ NF1 Polyclonal Antibody
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Product Code. 16609674
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Quantity:
100 μL
Unit Size:
100µL
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16609674 100 μL 100µL
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Product Code. 16609674 Supplier Invitrogen™ Supplier No. PA5103218

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NF1.

The protein encoded by this gene is a type I integral membrane protein localized in the intermediate region between the endoplasmic reticulum and the Golgi, presumably recycling between the two compartments. The protein is a mannose-specific lectin and is a member of a novel family of plant lectin homologs in the secretory pathway of animal cells. Mutations in the gene are associated with a coagulation defect. Using positional cloning, the gene was identified as the disease gene leading to combined factor V-factor VIII deficiency, a rare, autosomal recessive disorder in which both coagulation factors V and VIII are diminished.
TRUSTED_SUSTAINABILITY

Specifications

Antigen NF1
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NF1
Gene Accession No. P21359, P97526, Q04690
Gene Alias AW494271; DKFZp686J1293; E030030H24Rik; FLJ21220; neurofibromatosis 1; Neurofibromatosis type 1; neurofibromatosis-related protein NF-1; Neurofibromin; neurofibromin 1; Neurofibromin truncated; NF1; Nf-1; NFNS; VRNF; WSS
Gene Symbols NF1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NF1(Accession P21359), corresponding to amino acid residues S2802-V2839.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 18015, 24592, 4763
Target Species Human, Mouse, Rat, Monkey
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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