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NF2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

145.00€ - 410.00€

Specifications

Antigen NF2
Concentration 0.25 mg/mL
Applications Western Blot
Classification Polyclonal
Conjugate Unconjugated
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
16817183
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Proteintech
10659-1-AP-20UL
20 μL
145.00€
20µL
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16807183
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Proteintech
10659-1-AP-150UL
150 μL
410.00€
150µL
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Description

Description

Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF1 E3 ubiquitin-protein ligase complex (By similarity). Plays a role in lens development and is required for complete fiber cell terminal differentiation, maintece of cell polarity and separation of the lens vesicle from the corneal epithelium.
Specifications

Specifications

NF2
Western Blot
Unconjugated
Rabbit
Rat, Mouse, Human
P35240, P46662, Q63648
18016, 25744, 4771
NF2 Fusion Protein Ag1013
Primary
-20°C
NF2
0.25 mg/mL
Polyclonal
Liquid
RUO
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
ACN, BANF, Neurofibromin 2, neurofibromin 2 (merlin), NF2, SCH, Schwannomerlin, Schwannomin
Nf2
IgG
Antigen Affinity Chromatography
Antibody
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SDS
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Documents

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