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  6. Phospho-AKT (Ser473) Mouse anti-Human, Mouse, Clone: 1C10B8, Proteintech

Phospho-AKT (Ser473) Mouse anti-Human, Mouse, Clone: 1C10B8, Proteintech

Product Code. 16878325 Shop All Proteintech Products
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16878325 20 μL 20µL
16868325 100 μL 100µL
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Product Code. 16878325 Supplier Proteintech Supplier No. 664441IG20UL

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Description

Mouse Monoclonal Antibody

This antibody detects all the members of AKT with phospho-modification at Ser473.

The Akt family of serine/threonine protein kinases (also called protein kinase B/PKB) plays a key role in insulin signaling, cellular survival, and transformation. Akt1 is activated by phosphorylation on residues threonine 308 and Serine 473. Thr308, in the catalytic domain, is phosphorylated by the protein kinase PDK1, and Ser473, in the COOH-terminal regulatory domain, is phosphorylated by putative serine 473 kinase. To date, a couple of proteins have been shown to physically interact with PKB.

Specifications

Antigen Phospho-AKT (Ser473)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 1C10B8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene AKT1
Gene Accession No. P31749, P31750
Gene Alias AKT, AKT1, AKT1-phospho-S473, pakt, p-AKT, Phospho akt, PKB, PKB ALPHA, PRKBA, Protein kinase B, Proto oncogene c Akt, RAC, RAC ALPHA, RAC PK alpha
Gene Symbols AKT1
Host Species Mouse
Immunogen Peptide
Purification Method Protein G
Quantity 20 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11651, 207
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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