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Invitrogen™ Phospho-BIK (Thr33) Polyclonal Antibody

Description
Antibody detects endogenous levels of BIK only when phosphorylated at Threonine 33.
The Bik protein is known to interact with cellular and viral survival-promoting proteins, such as BCL2 and the Epstein-Barr virus in order to enhance programmed cell death. Because its activity is suppressed in the presence of survival-promoting proteins, this protein is suggested as a likely target for antiapoptotic proteins. This protein shares a critical BH3 domain with other death-promoting proteins, BAX and BAK.
Specifications
Specifications
| Antigen | Phospho-BIK (Thr33) |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Polyclonal |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.4 |
| Gene | BIK |
| Gene Accession No. | Q13323 |
| Gene Alias | apoptosis inducer NBK; apoptosis-inducing NBK; BBC1; BCL2 interacting killer; bcl-2-interacting killer; BCL2-interacting killer; BCL2-interacting killer (apoptosis-inducing); bhikhari; BIK; Bik-like killer protein; Biklk; BIP 1; BIP1; Blk; BP 4; BP4; cb 60; natural born killer; NBK |
| Gene Symbols | BIK |
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