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Invitrogen™ Phospho-Caveolin 1 (Tyr14) Polyclonal Antibody
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Product Code. 17752694
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Quantity:
100 μL
Unit Size:
100µL
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17752694 100 μL 100µL
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Product Code. 17752694 Supplier Invitrogen™ Supplier No. PA5121297

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Description

Rabbit Polyclonal Antibody

Positive test controls include: HeLa, NIH/3T3. The target is usually found in the following locations: Cell membrane, Golgi apparatus membrane, Membrane, Membrane raft, Peripheral membrane protein, caveola. Immunogen sequence: HLYTV.

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-Caveolin 1 (Tyr14)
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 1.31 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
Gene CAV1
Gene Accession No. P49817, Q03135
Gene Alias BSCL3; CAV; CAV1; Cav-1; caveolae; caveolin 1; caveolin 1, caveolae protein; caveolin 1, caveolae protein, 22kDa; caveolin 1a; caveolin 1b; caveolin caveolae protein 22 kDa; caveolin, caveolae protein 1; caveolin, caveolae protein, 22 kDa; caveolin-1; caveolin-1a; caveolin-1b; cell growth-inhibiting protein 32; CGL3; HGNC:1527; LCCNS; MSTP085; OTTHUMP00000196475; PPH3; Unknown (protein for IMAGE:7985573); variant a; variant b; vesicular integral-membrane protein VIP21; VIP21; wu:fc07c04
Gene Symbols CAV1
Host Species Rabbit
Immunogen A synthetic phosphorylated peptide around Y14 of human Caveolin-1 (NP_001744.2).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12389, 857
Target Species Human, Mouse
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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