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Invitrogen™ Phospho-DAPK1 (Ser308) Polyclonal Antibody
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Product Code. 16612235
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Quantity:
100 μL
Unit Size:
100µL
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16612235 100 μL 100µL
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Product Code. 16612235 Supplier Invitrogen™ Supplier No. PA5105788

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of DAPK1 only when phosphorylated at Ser308.

DAPK1 is a large, calmodulin-dependent kinase involved in gamma-interferon induced programmed cell death and is a potential tumor suppressor. DAPK1 is involved in multiple cellular signaling pathways that trigger cell survival, apoptosis, and authophagy. It regulates both type I apoptotic and type II autophagic cell death signal, depending on the cellular setting. Type I apoptotic cell death is caspase-dependent, type II authophagic cell death is caspase-independent. DAPK1 phosphorylates PIN1 resulting in inhibition of its catalytic activity, nuclear localization, and cellular function. It also phosphorylates TPM1, STX1A, PRKD1, BECN1, TSC2, RPS6, MYL9, and DAPK3.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-DAPK1 (Ser308)
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DAPK1
Gene Accession No. P53355, Q80YE7
Gene Alias D13Ucla1; DAP kinase 1; DAPK; DAPK1; DAP-Kinase; death associated protein kinase 1; death-associated protein kinase 1; DKFZp781I035; OTTHUMP00000216193
Gene Symbols DAPK1
Host Species Rabbit
Immunogen A synthesized peptide derived from human DAPK1(Accession P53355), corresponding to amino acid residues around phosphorylated Ser308.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1612, 306722, 69635
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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