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Invitrogen™ Phospho-DOK2 (Tyr345) Polyclonal Antibody
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Product Code. 17730144
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Quantity:
100 μL
Unit Size:
100µL
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17730144 100 μL 100µL
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Product Code. 17730144 Supplier Invitrogen™ Supplier No. PA5118727

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of DOK2 only when phosphorylated at Tyr345.

The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 from CML cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-DOK2 (Tyr345)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene DOK2
Gene Accession No. O60496, O70469
Gene Alias docking protein 2; docking protein 2, 56kD; docking protein 2, 56kDa; Dok2; Dok-2; DokR; Dok-R; dok-related protein; Downstream of tyrosine kinase 2; Frip; IL-Four Receptor Interacting Protein; IL-four receptor-interacting protein; LOW QUALITY PROTEIN: docking protein 2; docking protein 2; p56 dok-2; p56(dok-2); p56DOK; p56dok-2
Gene Symbols DOK2
Host Species Rabbit
Immunogen A synthesized peptide derived from human DOK2(Accession O60496), corresponding to amino acid residues around phosphorylated Tyr345.
Purification Method Sequential Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 13449, 9046
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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