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  6. Invitrogen™ Phospho-KSR1 (Ser392) Recombinant Rabbit Monoclonal Antibody (KSR1S392-3A4), FITC, Invitrogen™

Invitrogen™ Phospho-KSR1 (Ser392) Recombinant Rabbit Monoclonal Antibody (KSR1S392-3A4), FITC, Invitrogen™

Product Code. p-7215278 Shop All Thermo Scientific Products
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17196878 10 Tests Pack of 10
17146608 100 Tests Pack of 100
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Product Code. 17196878 Supplier Invitrogen™ Supplier No. MA537293

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Description

Rabbit Recombinant Monoclonal Antibody

Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases. Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2 (PubMed:29433126). Promotes activation of MAPK1 and/or MAPK3, both in response to EGF and to cAMP. Its kinase activity is unsure. Some protein kinase activity has been detected in vitro, however the physiological relevance of this activity is unknown. [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-KSR1 (Ser392)
Applications Flow Cytometry
Classification Recombinant Monoclonal
Clone KSR1S392-3A4
Conjugate FITC
Formulation PBS with 0.20% BSA and 0.09% sodium azide
Gene KSR1
Gene Accession No. Q61097, Q8IVT5
Gene Alias AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2
Gene Symbols KSR1
Host Species Rabbit
Immunogen A synthetic phospho-peptide corresponding to residue surrounding Ser392 of human phospho KSR1.
Purification Method Protein A/G
Quantity 10 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 16706, 8844
Target Species Human, Mouse
Content And Storage 4°C, store in dark
Product Type Antibody
Form Liquid
Isotype IgG κ
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