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Invitrogen™ Phospho-MYL12A (Ser1) Polyclonal Antibody
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Product Code. 17816848
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Quantity:
100 μL
Unit Size:
100µL
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17816848 100 μL 100µL
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Product Code. 17816848 Supplier Invitrogen™ Supplier No. PA5143726

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Description

Rabbit Polyclonal Antibody

The antibody detects a 20 kDa* band corresponding to the molecular weight of myosin light chain in human A431 treated with EGF or calyculin A. In addition, the antibody detects the 20 kDa myosin light chain in mouse C2C12, rat PC12, and rabbit fibroblasts treated with calyculin A.

This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-MYL12A (Ser1)
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Myl12a
Gene Accession No. P13832, P19105, Q5E9E2
Gene Alias 2900073G15Rik; AI838292; brain specific myosin regulatory light chain; C80200; Epididymis secretory protein Li 24; HEL-S-24; MLC-2; MLC20; MLC-2A; MLC-2B; MLCB; MRCL3; MRLC2; MRLC3; MYL12A; MYL12B; MYL2B; MYLC2B; myosin light chain 12A; myosin light chain, regulatory B-like; myosin regulatory light chain 12A; Myosin regulatory light chain 12B; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain 20 kDa; myosin regulatory light chain 2-A, smooth muscle isoform; Myosin regulatory light chain 2-B, smooth muscle isoform; myosin regulatory light chain 3; Myosin regulatory light chain MRLC2; Myosin regulatory light chain MRLC3; myosin regulatory light chain RLC-A; Myosin RLC; myosin RLC-A; myosin, light chain 12A, regulatory, non-sarcomeric; myosin, light polypeptide, regulatory, non-sarcomeric (20kD); NMDA receptor-interacting protein; RGD1309537; RLC; Rlc-a; SHUJUN-1
Gene Symbols Myl12a
Host Species Rabbit
Immunogen Phospho-MLC (Ser-1) synthetic peptide (coupled to KLH) corresponding to amino acid residues surrounding Ser-1 in bovine myosin regulatory light chain 9 (Myl9). This peptide sequence is highly conserved in human, rat, and mouse Myl9, and in other smooth muscle and non-muscle MLCs.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 10627, 501203, 531505, 67268
Target Species Human, Mouse, Rat, Bovine
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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