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Phospho-p130Cas (Tyr165) Polyclonal Antibody, Invitrogen™

Product Code. 15545301
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Quantity:
100 μg
Unit Size:
100µg
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15545301 100 μg 100µg
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Product Code. 15545301 Supplier Invitrogen Supplier No. PA538377

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Description

Rabbit Polyclonal Antibody

The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins. p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection. Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Phospho-p130Cas (Tyr165)
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene BCAR1
Gene Accession No. P56945, Q61140, Q63767
Gene Alias Breast cancer anti-estrogen resistance protein 1, CRK-associated substrate, Cas scaffolding protein family member 1, p130cas, BCAR1, CAS, CASS1, CRKAS
Gene Symbols BCAR1
Host Species Rabbit
Immunogen A synthetic phosphopeptide derived from human p130 Cas around the phosphorylation site of Tyr165 (D-L-YP-Q-V)
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12927, 25414, 9564
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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