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Invitrogen™ PRELP Polyclonal Antibody
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Product Code. 17782044
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Quantity:
100 μL
Unit Size:
100µL
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17782044 100 μL 100µL
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Product Code. 17782044 Supplier Invitrogen™ Supplier No. PA5120649

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Description

Rabbit Polyclonal Antibody

Positive test controls include: Mouse lung, Rat heart. Immunogen sequence: LDLQHNRLSD GVFKPDTFHG LKNLMQLNLA HNILRKMPPR VPTAIHQLYL DSNKIETIPN GYFKSFPNLA FIRLNYNKLT DRGLPKNSFN ISNLLVLHLS HNRISSVPAI NNRLEHLYLN NNSIEKINGT QICPNDLVAF HDFSSDLENV PHLRYLRLDG N.

PRELP is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage.
TRUSTED_SUSTAINABILITY

Specifications

Antigen PRELP
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 3.14 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
Gene PRELP
Gene Accession No. Q9EQP5, Q9JK53
Gene Alias 55 kDa leucine-rich repeat protein of articular cartilage; 7330409J17Rik; MST161; MSTP161; PRELP; Prolargin; prolargin proteoglycan; proline and arginine rich end leucine rich repeat protein; proline arginine-rich end leucine-rich repeat; proline/arginine-rich end leucine-rich repeat protein; proline-arginine-rich end leucine-rich repeat protein; SLRR2A
Gene Symbols PRELP
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 200-360 of human PRELP (NP_002716.1).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 116847, 84400
Target Species Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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