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Description
The antibody is specific to PTPRJ.
CD148 is a highly glycosylated transmembrane protein of up to 250 kDa, containing eight fibronectin type III domains in the extracellular region and one tyrosine phosphatase domain in the cytoplasmic region. Expression is found broadly on fibroblasts, epithelial cells, lymphocytes (B, T and NK cells), and myeloid cells (monocytes and granulocytes). CD148 can dephosphorylate proteins such as LAT and PLC-gamma, and is involved in the downregulation of T cell activation. Conversely, CD148 expression can be upregulated following T cell activation.
Specifications
Specifications
| Antigen | PTPRJ |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 0.19 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | PTPRJ |
| Gene Accession No. | Q12913 |
| Gene Alias | CD148, Density enhanced phosphatase 1, DEP 1, DEP1, HPTP eta, HPTPeta, PTPRJ, R PTP ETA, R PTP J, SCC1 |
| Gene Symbols | PTPRJ |
| Show More |
Product Title
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