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Quinine hemisulfate monohydrate, 98+%

Code produit. 11468896
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Quantity:
10 g
50 g
250 g
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10g
250g
50g
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Code produit. 11468896

missing translation for 'mfr': Thermo Scientific Alfa Aesar A17036.30

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Description

CAS: 6119-70-6 | C40H54N4O10S | 782.95 g/mol

Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Solubility
Soluble in a mixture of chloroform and absolute alcohol (2:1).

Notes
Light sensitive. Incompatible with strong oxidizing agents, alkalis, ammonia, strong bases and iodine.
TRUSTED_SUSTAINABILITY

Identifiants chimiques

CAS 6119-70-6
Molecular Formula C40H54N4O10S
Molecular Weight (g/mol) 782.95
MDL Number MFCD00150790
InChI Key ZHNFLHYOFXQIOW-OIGVVMIYNA-N
Synonym Quinine sulfate (2:1) (salt) dihydrate; Quinine sulfate dihydrate
PubChem CID 134129495
IUPAC Name (R)-[(2R,4R,5R)-5-ethenyl-1-azabicyclo[2.2.2]octan-2-yl]-(6-methoxyquinolin-4-yl)methanol;sulfuric acid;tetrahydrate
SMILES O.O.OS(O)(=O)=O.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C.[H][C@@]1(CN2CCC1C[C@@]2([H])[C@H](O)C1=C2C=C(OC)C=CC2=NC=C1)C=C

Spécification

Melting Point 217°C to 218°C (decomposition)
Odor Odorless
Quantity 250 g
Beilstein 6113937
Sensitivity Light sensitive
Merck Index 14,8061
Solubility Information Soluble in a mixture of chloroform and absolute alcohol (2:1).
Optical Rotation −241° (c=2 in 0.1M HCl)
Formula Weight 391.47 (373.46 Anhydrous)
Percent Purity 99%
Chemical Name or Material Quinine hemisulfate monohydrate
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