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Invitrogen™ RGS10 Polyclonal Antibody
Description
Immunogen sequence: MFNRAVSRLS RKRPPSDIHD SDGSSSSSHQ SLKSTAKWAA SLENLLEDPE GVKRFREFLK KEFSEENVLF WLACEDFKKM QDKTQMQEKA KEIYMTFLSS KASSQVNVEG QSRLNEKILE EPHPLMFQKL QDQIFNLMKY DSYSRFLKSD LFLKHKRTEE EEEDLPDAQT AAKRASRIYN T; Positive Samples: HeLa, HepG2, HT-1080, Jurkat, Rat brain.
RGS10 inhibits signal transduction by increasing the GTPASE activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. It associates specifically with the activated forms of the G protein subunits G(I)-ALPHA and G(Z)- alpha but fails to interact with the structurally and functionally distinct G(S)-alpha subunit. Activity on G(Z)-alpha is inhibited by palmitoylation of the G-protein.
Specifications
Specifications
| Antigen | RGS10 |
| Applications | ELISA, Western Blot |
| Classification | Polyclonal |
| Concentration | 1.74 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | RGS10 |
| Gene Accession No. | O43665, P49806, Q9CQE5 |
| Gene Alias | 2310010N19Rik; regulator of G protein signaling 10; regulator of G-protein signaling 10; regulator of G-protein signalling 10; Rgs10; similar to Regulator of G-protein signaling 10 (RGS10) |
| Gene Symbols | RGS10 |
| Show More |
Product Title
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