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Invitrogen™ RNF111 Polyclonal Antibody
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Product Code. 17761364
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Quantity:
100 μL
Unit Size:
100µL
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17761364 100 μL 100µL
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Product Code. 17761364 Supplier Invitrogen™ Supplier No. PA5119964

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Description

Rabbit Polyclonal Antibody

Positive Control: K562 cell lysate, 293T cell lysate, Hela cell lysate, human placenta tissue. Subcellular Location: Cytoplasm, Nucleus, PML body.

The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF111
Applications Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.2% BSA, 50% glycerol and 0.05% sodium azide; pH 7.4
Gene RNF111
Gene Accession No. Q6ZNA4
Gene Alias ARK; Arkadia; E3 ubiquitin-protein ligase Arkadia; hRNF111; ring finger 111; RING finger protein 111; RING-type E3 ubiquitin transferase Arkadia; Rnf111
Gene Symbols RNF111
Host Species Rabbit
Immunogen Recombinant protein within human RNF111 aa 795-994.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54778
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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