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Invitrogen™ RNF157 Polyclonal Antibody

Product Code. 15792471 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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15792471 100 μL 100µL
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Product Code. 15792471 Supplier Invitrogen™ Supplier No. PA554544

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Description

Rabbit Polyclonal Antibody

Immunogen sequence: KSLSKSTSQN SSVLHEEEDE HSCSESETQL SQRPSVQHLG EECGVTPESE NLTLSSSGAI DQSSCTGTPL SSTISSP Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 86%.

E3 ubiquitin ligase that ubiquitinates APBB1 for its degradation by the proteasome and thus prevents apoptosis and promotes survival of neurons (PubMed:25342469). Has a dual role in neurons as it is also required for dendrite growth and maintenance for which its ligase activity is not critical (PubMed:25342469). May act as a scaffold molecule to regulate this process (PubMed:25342469). Acts as a downstream effector of the interconnected PI3K and MAPK signaling pathways and thus participates in the regulation of the cell cycle (PubMed:28655764). [UniProt].
TRUSTED_SUSTAINABILITY

Specifications

Antigen RNF157
Applications Immunohistochemistry (Paraffin), Immunocytochemistry
Classification Polyclonal
Concentration 0.05 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene RNF157
Gene Accession No. Q96PX1
Gene Alias 2610036E23Rik; A130073L17Rik; E3 ubiquitin ligase RNF157; KIAA1917; mKIAA1917; ring finger protein 157; RING-type E3 ubiquitin transferase RNF157; RNF157
Gene Symbols RNF157
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human RNF157. Recombinant protein control fragment (Product #RP-93306).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 114804
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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