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Invitrogen™ RRAS2 Polyclonal Antibody
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Product Code. 16680535 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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16680535 100 μL 100µL
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Product Code. 16680535 Supplier Invitrogen™ Supplier No. PA5104087

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total RRAS2.

RRAS2 is involved in activating mutations and the overexpression of classical Ras subfamily members (K-RAS, N-RAS and H-RAS) have been widely investigated as key events in the development of human cancers. The RRAS subfamily of Ras-related proteins includes RRAS1, RRAS2 (TC21) and RRAS3 (M-Ras) show overall amino acid identity with the classical Ras subfamily (H-Ras, K-Ras and N-Ras) of 55-60%. RRAS2 is a small GTP binding protein of the Ras superfamily of GTPases. It might transduce growth inhibitory signals across the cell membrane, exerting its effect through an effector shared with the Ras proteins. RRAS2 has high oncogenic potential and overexpression/mutations have been reported in several tumor tissues and cell lines.
TRUSTED_SUSTAINABILITY

Specifications

Antigen RRAS2
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene RRAS2
Gene Accession No. P62070, P62071
Gene Alias 2610016H24Rik; C86394; Ras-like protein TC21; ras-related protein R-Ras2; related RAS viral (r-ras) oncogene homolog 2; Rras2; TC21; Teratocarcinoma oncogene
Gene Symbols RRAS2
Host Species Rabbit
Immunogen A synthesized peptide derived from human RRAS2(Accession P62070), corresponding to amino acid residues V164-F204.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 22800, 365355, 66922
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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