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SH3BP5 Mouse, anti-Human, Unconjugated, Clone: 1B9D4, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 67841-1-IG-150UL

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Product Code. 17201506

  • 410.00€ / 150µL

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Description

Description

SH3BP5(SH3 domain-binding protein 5) is also named as SAB. It is previously isolated in a screen for proteins capable of binding to the Src homology 3 (SH3) domain of Bruton's tyrosine kinase (Btk) and could play a role in targeting JNK and Btk to mitochondria and/or mediating cross-talk between the JNK and Btk signalling pathways. It has 2 isoforms produced by alternative splicing with the molecular mass of 50 kDa and 32 kDa. There are two bands of 83 kDa and 70 kDa can be detected in A431 and the larger species may correspond to splice variants of SH3BP5 or SH3BP5 proteins that have undergone post-translational modification(PMID:12167088). In addition, we detect the band of 32 kDa as the isoform 2 of SH3BP5 and another band of 62 kDa besides the 47 kDa and 80 kDa.

Specifications

Specifications

SH3BP5
Monoclonal
1000 μg/mL
Mouse
Primary
Human, Mouse, Rat, Pig, Chicken
Western Blot, ELISA
1B9D4
Unconjugated
150 μL
9467
Liquid
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