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Invitrogen™ TRPC4AP Polyclonal Antibody
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Product Code. 16622885 Shop All Thermo Scientific Products
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Quantity:
100 μL
Unit Size:
100µL
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16622885 100 μL 100µL
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Product Code. 16622885 Supplier Invitrogen™ Supplier No. PA5106444

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TRPC4AP.

Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control. The DCX(TRUSS) complex specifically mediates the polyubiquitination and subsequent degradation of MYC. Also participates in the activation of NFKB1 in response to ligation of TNFRSF1A, possibly by linking TNFRSF1A to the IKK signalosome. Involved in JNK activation via its interaction with TRAF2. Also involved in elevation of endoplasmic reticulum Ca(2+) storage reduction in response to CHRM1.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TRPC4AP
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TRPC4AP
Gene Accession No. Q8TEL6, Q9JLV2
Gene Alias 4833429F06Rik; C20orf188; D2Ertd113e; hypothetical protein; mFLJ00177; PPP1R158; protein phosphatase 1, regulatory subunit 158; Protein TAP1; Protein TRUSS; Rabex-5/Rin2-interacting protein; short transient receptor potential channel 4 associated protein; short transient receptor potential channel 4-associated protein; TAP1 protein; TNF-receptor; TNF-receptor ubiquitous scaffolding/signaling protein; TP4AP; transient receptor potential cation channel subfamily C member 4 associated protein; transient receptor potential cation channel, subfamily C, member 4 associated protein; transient receptor protein 4, associated protein; TRP4-associated protein; Trp4-associated protein TAP1; Trpc4ap; trpc4-associated protein; Trrp4ap; TRUSS; tumor necrosis factor receptor-associated ubiquitous scaffolding and signaling protein
Gene Symbols TRPC4AP
Host Species Rabbit
Immunogen A synthesized peptide derived from human TRPC4AP(Accession Q8TEL6), corresponding to amino acid residues V6-Q56.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26133, 362247, 56407
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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