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Invitrogen™ TUSC2 Polyclonal Antibody
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Product Code. 16647554
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Quantity:
100 μL
Unit Size:
100µL
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16647554 100 μL 100µL
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Product Code. 16647554 Supplier Invitrogen™ Supplier No. PA5101075

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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TUSC2.

TUSC2 (tumor suppressor candidate 2), also known as FUS1, LGCC or PDAP2, is a 110 amino acid protein that is expressed at high levels in kidney, pancreas, lung, heart and skeletal muscle where it is thought to function as a tumor suppressor. More specifically, TUSC2 inhibits invasive colony formation by inducing G1 cell cycle arrest and ultimately causing apoptosis, thereby preventing tumor growth. The gene encoding TUSC2 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TUSC2
Applications Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TUSC2
Gene Accession No. O75896, Q9WVF8
Gene Alias 1190001E22Rik; AA407686; C3orf11; Fus1; Fus-1 protein; Fusion 1 protein; Lgcc; lung cancer candidiate, FUS; PAP; PDAP2; PDGFA associated protein 2; PDGFA-associated protein 2; Tumor suppressor candidate 2; TUSC 2; Tusc2
Gene Symbols TUSC2
Host Species Rabbit
Immunogen A synthesized peptide derived from human TUSC2(Accession O75896), corresponding to amino acid residues F52-D102.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11334, 80385
Target Species Human, Mouse
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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