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  6. von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody,Lab Vision™ Epredia™

Product Code. 12672037 Shop All Epredia Products
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Quantity:
100 μL
200 μL
500 μL
1 mL
Conjugate:
Biotin
Unconjugated
Concentration:
1mg/mL
200μg/mL
Unit Size:
100µL
1mL
200µL
500µL
7 product options available for selection
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Product Code. Quantity Conjugate Concentration unitSize
12672037 500 μL Unconjugated 200μg/mL 500µL
12632037 100 μL Biotin 200μg/mL 100µL
12642037 500 μL Biotin 200μg/mL 500µL
12662037 100 μL Unconjugated 200μg/mL 100µL
12652037 1 mL Unconjugated 200μg/mL 1mL
12682037 100 μL Unconjugated 1mg/mL 100µL
12692037 200 μL Unconjugated 1mg/mL 200µL
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This item is not returnable. View return policy
Product Code. 12672037 Supplier Epredia Supplier No. MS690P1

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Description

Provide accurate, reproducible results with the Epredia™ von Hippel-Lindau (vHL) Protein Ab-1, Mouse Monoclonal Antibody.

Molecular genetic studies suggest that VHL is a tumor-suppressor gene. Alterations in the von Hippel-Lindau (VHL) gene are correlated with a diverse group of neoplasms including hemangioblastoma, clear cell renal carcinoma (RCC), and pheochromocytoma. Two transcriptional elongation factors, Elongin B and C, are shown to bind in vitro and in vivo to a short, colinear region of the VHL protein (pVHL) that is frequently mutated in human tumors. It is proposed that pVHL functions in vivo as a negative regulator of transcription elongation.

Host Species: Mouse

Clone: Ig33

Isotype: IgG1/κ

Species Reactivity: Human and Mouse. Others not known.

Epitope: aa 1-54

Immunogen: A recombinant protein containing aa 1-213 of human vHL

Molecular Weight: 30kDa

Positive Control: Kidney

Cellular Localization: Cytoplasmic Ab-1 does not recognize the truncated form of VHL protein.

Note:

USA: RUO; Int'l: RUO

TRUSTED_SUSTAINABILITY

Specifications

Antigen von Hippel-Lindau (vHL) Protein Ab-1
Classification Monoclonal
Clone Ig33
Concentration 200μg/mL
Conjugate Unconjugated
Host Species Mouse
Immunogen A recombinant protein containing aa 1-213 of human VHL
Quantity 500 μL
Regulatory Status RUO
Research Discipline Cancer and Tumor Biology
Primary or Secondary Primary
Target Species Human, Mouse
Form Concentrated
Isotype IgG2a κ
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