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Invitrogen™ ZNF384 Polyclonal Antibody

Description
Positive test controls include: HeLa, Rat thymus. The target is usually found in the following locations: Nucleus. Immunogen sequence: MEESHFNSNP YFWPSIPTVS GQIENTMFIN KMKDQLLPEK GCGLAPPHYP TLLTVPASVS LPSGISMDTE SKSDQLTPHS.
This gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene.
Specifications
Specifications
| Antigen | ZNF384 |
| Applications | ELISA, Immunohistochemistry (Paraffin), Western Blot |
| Classification | Polyclonal |
| Concentration | 1.68 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3 |
| Gene | ZNF384 |
| Gene Accession No. | Q8TF68, Q9EQJ4 |
| Gene Alias | BB163993; C130073D16Rik; CAG repeat protein 1; CAGH1; CAGH1A; Cas-associated zinc finger protein; Cas-interacting zinc finger protein; Ciz; ERDA2; expanded repeat domain, CAG/CTG 2; NMP4; NP; nuclear matrix protein 4; Nuclear matrix transcription factor 4; TNRC1; Trinucleotide repeat-containing gene 1 protein; Zfp384; Zinc finger protein 384; Znf384 |
| Gene Symbols | Zfp384, ZNF384 |
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